| Date | Location | Result | |
| 03/04/06 | Alumni Arena (Buffalo, NY) | Toledo 70, Buffalo 58 | Box score |
| 02/28/06 | Alumni Arena (Buffalo, NY) | Kent State 73, Buffalo 59 | Box score |
| 02/25/06 | Alumni Arena (Buffalo, NY) | Buffalo 72, Akron 62 | Box score |
| 2/21/06 | Athens, Ohio (Convocation Center) | Buffalo 84, Ohio Bobcats 77 | Box score |
| 2/18/06 | Anderson Arena; Bowling Green, Ohio | Bowling Green 65, Buffalo 51 | Box score |
| 02/14/06 | Alumni Arena (Buffalo, NY) | Buffalo 62, Miami 61 | Box score |
| 2/11/06 | Kalamazoo, Michigan/University Arena | Western Michigan University 86, Buffalo 42 | Box score |
| 02/08/06 | Alumni Arena (Buffalo, NY) | Central Michigan 58, Buffalo 50 | Box score |
| 2/4/06 | Worthen Arena - Muncie, Ind. | Ball State Cardinals 70, Buffalo Bulls 56 | Box score |
| 01/31/06 | NIU Convocation Center | Northern Illinois 81, Buffalo 72 | Box score |
| 01/28/06 | Alumni Arena (Buffalo, NY) | Eastern Michigan 56, Buffalo 41 | Box score |
| 01/25/06 | Alumni Arena (Buffalo, NY) | Toledo 57, Buffalo 47 | Box score |
| 01/21/06 | M.A.C. Center [Kent, Ohio] | Kent State 73, Buffalo 56 | Box score |
| 1/18/06 | Rhodes Arena- Akron, Ohio | Buffalo 68, AKRON 63 | Box score |
| 01/14/06 | Alumni Arena (Buffalo, NY) | Ohio 72, Buffalo 62 | Box score |
| 01/10/06 | Alumni Arena (Buffalo, NY) | Bowling Green 75, Buffalo 48 | Box score |
| 01/07/06 | Millett Hall; Oxford, OH | Buffalo 78, Miami U. 75 | Box score |
| 12/31/05 | San Antonio, Texas (Convocation Center) | Tulsa 64, Buffalo 39 | Box score |
| 12/30/05 | San Antonio, Texas (Convocation Center) | Buffalo 73, Texas-San Antonio 62 | Box score |
| 12/28/05 | Alumni Arena (Buffalo, NY) | Bucknell 74, Buffalo 63 | Box score |
| 12/20/05 | Rochester, Mich. (O'Rena) | Oakland 82, Buffalo 80 | Box score |
| 12/18/05 | Alumni Arena (Buffalo, NY) | Buffalo 87, Northeastern 59 | Box score |
| 12/07/05 | Alumni Arena (Buffalo, NY) | Buffalo 53, Youngstown State 40 | Box score |
| 12/03/05 | Niagara Un., N.Y. Gallagher Center | Buffalo 68, Niagara 45 | Box score |
| 11/30/05 | Easton, Pa. -- Kirby Sports Center | Buffalo 66, Lafayette 56 | Box score |
| 11/22/05 | Alumni Arena (Buffalo, NY) | Auburn 70, Buffalo 41 | Box score |
| 11/20/05 | Alumni Arena (Buffalo, NY) | Syracuse 64, Buffalo 63 | Box score |
| 11/18/05 | Alumni Arena (Buffalo, NY) | Canisius 77, Buffalo 61 | Box score |